Monday 30 July 2007

QTc in type 1 diabetics

The EURODIAB Prospective Complications Study group has assessed the incidence and risk factors of prolonged QTc in people with type 1 diabetes. They studied 1,415 type 1 diabetic subjects, who had normal QTc at baseline. The QTc was reanalysed after the 7-year follow-up period. QTc >0.44 s was considered abnormally prolonged.
The predictive factors for prolonged QTc interval were female sex, A1C, and systolic blood pressure. Physical activity and BMI within the range of 21.5–23.2 kg/m2 played a protective role

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